Gout can cause kidney damage?

Gout kidney damage can occur. According to statistics, gout patients 20% -25% of uric acid nephropathy, and the autopsy confirmed the kidney lesions were almost 100%. It includes gouty nephropathy, acute obstructive nephropathy and urolithiasis. (1) gouty nephropathy sustainability of hyperuricemia, 20% in clinical nephropathy on the performance, after several years or more may have a glomerular and tubular damage to a small number of developing uremia. Uric acid salt nephropathy after the incidence of gout of joint damage, and close relationship with the course and treatment. Studies show that uric acid salt nephropathy and gouty arthritis unrelated to the severity of that mild arthritis patients may have nephropathy, and serious kidney arthritis patients is not necessarily abnormal. Early mild unilateral or bilateral flank pain, swelling and later appeared mild to moderate hypertension. Urine was acidic, intermittent or persistent proteinuria, generally no more than + +. Renal tubular function has concentrated almost fell, a nocturnal enuresis, polyuria, urine relatively low density. About 5-10 years after nephropathy increase, in turn developed into uremia, about 17% -25% died of renal failure. (2) urinary calculi gout patients were acidic urine, thus urinary uric acid concentrations increase, the smaller stones from the urine, but often without feeling, urine sediments shows that the small brown sand; larger obstructive ureteral stones can be caused hematuria and renal colic due to a urinary infection secondary to renal impeded glenoid nephritis. Huge stones can cause renal calyceal deformed pelvis, hydronephrosis. Uric acid stones X line simply does not contrast, when uric acid, sodium and calcium X Online Visibility stone shadow. (3) acute obstructive nephropathy found in serum uric acid and uric acid in urine increased significantly, it is because of the influx extensive crystallization of uric acid caused by tubular obstruction. Gout often and hypertension, hyperlipidemia, atherosclerosis, coronary heart disease and type 2 diabetes. In older people Gout causes of death, cardiovascular factors far more than renal insufficiency. But between gout and cardiovascular disease there is no direct causal link, but both obesity, dietary factors are related.