Wednesday, November 7, 2007

Why hepatitis patients with fatty liver

Acute hepatitis longer period of time due to the decreased appetite, can cause malnutrition, caloric, lack of protein, vitamins and choline, such as methionine to lipid substances can cause protein, caloric malnutrition fatty liver. The severely damaged liver cells, liver cells in fat decomposition and oxidation decreased, the result neutral fat accumulation in liver cells, is also the cause of fatty liver. Viral hepatitis, liver cell degeneration its smooth endoplasmic reticulum membrane degradation to network or mass, rough endoplasmic reticulum is reduced, such as expansion with threshing. The smooth endoplasmic reticulum function is complex, and lipoprotein synthesis, and free fatty acids were related to the activation. Intrahepatic often accompanied by inflammation of the liver microcirculation and cell proliferative changes in the liver cells to induce some hypoxia, ischemia, cells and blood oxygen-containing material exchange between insufficient to reduce hepatic fatty acid oxidation. These changes have meant that the intrahepatic more xylanase and ATP decreased hepatic lipoprotein synthesis decreased triglyceride and apolipoprotein a combination of obstacles, the output decline in triglyceride accumulation in the liver and fatty liver. The recovery in hepatitis, a significant increase in appetite, caloric surplus that is stored in the form of fat in case of obesity, followed fatty liver. This is a certain relationship between obesity. Obese "excessive intake of fatty liver" in the real mechanism of caloric food is not high, with a relative lack of protein and choline, if only to patients with high fever and additional cards protein dietary choline, does not make fatty liver removed and glucose metabolism and the mechanism of the disorder. Therefore fatty liver hepatitis merger also may be due to medical personnel in the course of treatment of hepatitis positive Hugan treatment, the large number of long-term intravenous glucose, excessive restrictions on activities, high-calorie diet for the results.

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