Stone suffering from gout arthritis and chronic gout patients more chronic in vivo
crystallization of uric acid deposition will be in the cartilage and synovial membrane, and
soft tissue, the formation of tophi, and the blood uric acid concentrations higher, the
sick, the longer the period, it may be deposition of the more tophi, and sometimes will
affect vascular with the kidney, causing serious renal failure, nephrotic more serious and
difficult to create a vicious cycle of uric acid excretion, tophi sedimentary the more.
Often the site of deposition tophi many, including the ears, hands, elbow, Achilles tendon,
ankle or toe, and sometimes even lead to partial ulcer and difficult healing, or even to
accept the latest addition to surgery. Serious patients and cause deformation or chronic
joint symptoms, severe deformation of the foot may cause the patient wears shoes when the
serious problem. Moreover, the risk of kidney stones occur with increased serum uric acid
concentrations increase, and they often cause nephropathy, renal failure may need to
receive hemodialysis, this is cause gout patients died one of the main causes of death.
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