Wednesday, November 7, 2007

A summary of interstitial nephritis and classification

A tubular interstitial nephritis is a group of various reasons caused by the kidney disease. Major violations of tubular lesions and renal interstitial; clinical renal tubular dysfunction to its outstanding performance. According to the course, a tubular interstitial nephritis acute and chronic can be divided into two categories; there by infectious etiology, drugs, and genetic immune-mediated metabolism caused by obstacles such as interstitial nephritis. Clinical those caused by drugs for the most common, followed by urinary tract obstruction with the complexity of those caused chronic pyelonephritis. Its main diagnosis is based on: (1) patients with history of drug use or a history of chronic pyelonephritis. (2) In early disease glomerular diseases generally not the clinical features, such as, edema, hypertension, etc, and renal tubular dysfunction occurred in the earlier and glomerular dysfunction and disproportionate. In addition, renal dysfunction without hypertension, and the increase in mild proteinuria. Given the more than 90 percent of tubular interstitial nephritis one belonging to cure the cause, early diagnosis is crucial, even if the occurrence of renal dysfunction has been the patient, if discovered and promptly handle reversible factors (such as urinary obstruction, infection, etc.), can also suspend its development, and even improve kidney functional.

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