What is thromboangiitis obliterans?

Thromboangiitis obliterans (thromboangitis obliterans) for chronic peripheral vascular stenosis or occlusion disease. Also known as Berger's disease. Many occur in young and middle-aged men, many severe, tobacco history. The typical clinical manifestations of intermittent claudication, rest pain and migratory Thrombophlebitis. Major violations of the disease limbs, particularly the lower extremity, and its accompanying small artery and the vein superficial vein, the involvement of vascular vessel wall has full thickness of non-suppurative inflammation, thrombosis within lumen, sexual lumen showed complete occlusion and stenosis, caused limb ischemia caused pain, serious acromegaly the healing can occur difficult ulcer and gangrene. Symptomatic treatment can be used vasodilator drugs, analgesics, if necessary, conduct various kinds of surgery. Pathological etiology Thromboangiitis obliterans is an artery and vein young adults a cyclical, segmental inflammatory lesions. Most lesions of the blood vessels in the limbs, especially for the common lower extremity. First is the pathological changes of vascular endometrial thickening, and then there thrombosis, hence resulting in the final vascular complete obstruction. Usually disease first seen in the distal limb arteries, such as the tibia, anterior tibial, feet radius, arch, fortune arch, the toes, saying that such artery lesions involving only the further development of femoral artery and the brachial artery, and so on. Segmental lesions and normal part of the boundary between very clear, often accompanied vein involvement at the same time are generally lighter. Advanced, a fibrous tissue perivascular proliferation sclerosis. Clinical manifestations Almost all patients were men, aged 25 to 45 years old, the course slow. Typical symptoms are intermittent break trip with limb cold, numbness, tingling. There is continuous toe pain, especially when exacerbated bed at night (still pain). Late foot gangrene and ulcers. Imaging Findings Arteriography can show that the limbs artery occlusion site and collateral circulation, with arteriosclerosis obliterans of the performance is quite similar. In thromboangiitis obliterans, arteriography lumen can be found in small change to a section of the latter part of a complete vascular occlusion. On the lumen occlusion in a smooth, without filling defects phenomenon, not a distortion of its vessels were. Mai Guan Yan and thrombotic occlusion live with arteriosclerosis obliterans can produce collateral circulation. Differential diagnosis Take the identification of arteriosclerosis obliterans. Some people think that in thromboangiitis obliterans, collateral circulation vessels are numerous, but smaller, the effective degree of arteriosclerosis obliterans better.