Children with idiopathic thrombocytopenic purpura

[Outlined]
Idiopathic thrombocytopenic purpura (ITP) is common in children of hemorrhagic disease. After 40 years of research proves that this disease and immune-related, are considered to be an autoimmune disease. Clinical to skin, mucous membrane characterized spontaneous bleeding, infection prevalence before history, as indicated respiratory tract infection (cold). The acute and chronic disease divided into two types, mostly children with acute idiopathic thrombocytopenic purpura, acute phase may all ages ITP incidence, but common to infants period, the incidence of the spring high. The disease in children with acute type in about 80 ￣ 90% in the six months rehabilitation, 10 ￣ 25% to chronic. Chronic cases was particularly prevalent in school-aged children, course in more than six months, about 1 / 3 ￣ 1 / 2 to five years resumed. Individual cases of acute severe bleeding may occur (especially intracranial hemorrhage) and leading to death
[Symptoms of the disease]
1. Disease before 1 ￣ six weeks virus infection, as indicated respiratory infections, measles, chicken pox, etc.. 2. Sudden onset, severe bleeding, skin, mucous membrane bleeding spontaneously mainly for common skin, oral mucosa, gums and eye conjunctiva, nasal cavity and trauma site. Gastrointestinal tract, urinary tract bleeding rare, occasionally intracranial hemorrhage. 3. See needle point-like skin bleeding, bruising, a few cases of mild hepatosplenomegaly.
[Diagnosis]
1. Repeatedly laboratory examination platelet count decrease. 2. Spleen does not increase or slightly increase. 3. Bone marrow examination megakaryocyte cells increased or normal, mature obstacles. 4. Below 5:00 in which two points should be: (1) prednisone therapy effective. (2) the splenectomy treatment effective. (3) PAIg increased. (4) PAC3 increased. (5) determination of platelet shortened life expectancy. 5. Exclusion of secondary thrombocytopenia.
[Treatment principle]
1. Bed rest and avoid injury. 2. Prevent and control infection. 3. Positive control bleeding. 4. Necessary, surgical treatment.
[Evaluation]
1. Cure: no bleeding, platelet count> 100 × 1000000000 / L, sustained more than three months. No recurrence. 2. Turn for the better: hemorrhage disappeared or improved platelet rose to 20 ￣ 50 × 1000000000 / L, but did not reach 100 × 1000000000 / L, continuous inspection three or observation two weeks more. 3. Surprised me: bleeding symptoms did not improve or worsen, and platelet count were not improved standards.
[The expert suggested that]
Pediatric if epistaxis, bleeding gums, skin bleeding, should immediately to the hospital for an examination. Once a patient thrombocytopenia best system further examination and treatment. Outpatient treatment of patients must be advised by doctors to do so as not to endanger children with serious bleeding lives, we must pay attention to the following points: (1) to restrict the activities of the best bed rest and avoid injury; (2) eat easily digested food, dry , uncompromising, and a sting Do not eat food, so as not to cause injury mucosal bleeding, (3) avoid application of aspirin, dipyridamole, and other drugs, (4) attention to the prevention of infection (such as the flu), so as not to add to improve the condition again .