Chronic adrenal hypofunction

Bilateral adrenal when most of the damage, there are all sorts of glucocorticoid inadequate performance, saying adrenal hypofunction. There are primary and secondary. Primary chronic adrenal hypofunction also known as Addison disease, relatively rare; secondary Visibility hypothalamus - patients with pituitary dysfunction, as CRF or inadequate secretion of ACTH, which adrenal atrophy.
Etiology:
First, adrenal tuberculosis only bilateral adrenal tuberculosis, the majority of adrenal tissue damaged before clinical symptoms arise. With more than lung, bone or other parts of TB lesions. During the 1950s about chronic adrenal hypofunction in half in recent years, with the control of TB is diminishing. Second, autoimmune disorder idiopathic autoimmune reaction caused adrenal atrophy as the most common reason for the present, can often be measured in serum anti-adrenal tissue antibodies to. The main transgression and fascicular zone cells, antigen mainly in microsomes and mitochondria within. Many of the disease associated with other autoimmune disorders. If multiple endocrine gland dysfunction syndrome (Schmidt syndrome), may include, for example adrenal dysfunction, hypothyroidism, hypoparathyroidism, gonadal failure, diabetes, pituitary dysfunction, gastric parietal cell antibody positive, pernicious anemia, thyroid Gong can hyperthyroidism, colon tumor, myasthenia gravis, solitary red cell aplasia, and so on. Three other adrenal cancer metastasis, or tumor metastasis in patients with 10% of the bilateral adrenal metastasis to lung cancer and breast cancer as common. Can also be found in bilateral adrenal after resection, systemic fungal infection, such as adrenal amyloidosis.