Atrophic gastritis can cause pernicious anemia

Giant red blood cell anemia David in that one type of pernicious anemia. The reason why this type of anemia known as "vicious" is that it apart from the general weakness of anemia, tinnitus, lightheadedness, heart palpitations, shortness of breath, dizziness and fatigue, and other symptoms, but also a characteristic change in three areas: ① tongue pain, Tongues smooth, tongue nipple atrophy, as well as tongue such as lean beef. ② limbs, weakness, ataxia, standing instability, abnormal tendon reflexes and forgetful, easily agitated and psychiatric disorders damage to the nervous system performance. ③ varying degrees of hepatosplenomegaly. Pernicious anemia is the fundamental reason for vitamin B12 deficiency, due to lack of dietary vitamin B12 and incidence are extremely rare, and almost all of the gastrointestinal dysfunction, which is first and foremost the most common causes of chronic atrophic gastritis. Because vitamin B12 must be secretion of gastric parietal cells "factor" of combining a complex, in "factor" can be under the protection of smooth absorption. While patients with chronic atrophic gastritis gastric atrophy, resulting "factor" of the lack of secretion, and intestinal not absorb vitamin B12, which led to pernicious anemia. Atrophic gastritis and inflammation can be divided into gastric antral gastritis. Now that rarely found in pernicious anemia in patients with gastric antral gastritis, gastric and to the main body gastritis. Against atrophic gastritis with pernicious anemia the relationship between the symptoms if they develop pernicious anemia, should carefully check for atrophic gastritis. Once clear of pernicious anemia due to atrophic gastritis, stomach illness should be treated on the basis of intramuscular injection of vitamin B12, can begin delivery 100 micrograms daily; Two weeks later renamed the weekly two consecutive four weeks; Question blood resumes normal weekly injection 1st, as a maintenance treatment. It must be stressed that yes, pernicious anemia patients need long-term treatment of vitamin B12 to maintain.