Clinical acute fatty liver of pregnancy performance

There are two kinds of liver disease during pregnancy: a pregnancy and is a causal relationship between liver disease, liver disease that is caused by the pregnancy, such as gestational hypertension caused by secondary liver injury, intrahepatic cholestasis of pregnancy and acute fatty liver of pregnancy; Another situation is pregnant with liver disease, such as viral hepatitis, drug-induced liver disease, liver disease such can also occur in non-pregnant. More acute fatty liver of pregnancy occurred in the early young maternal morbidity time focused on pregnancy 28 ~ 40 weeks, an average of 36 weeks, then a few cases. Past statistics show that the acute fatty liver of pregnancy incidence rate of 1 in 10,000, maternal and child mortality rate as high as 85 percent. Recent trends in incidence rates have increased, the maternal and child mortality is down significantly. Acute fatty liver of pregnancy causes have not yet clear, pregnancy hormones may be related to metabolic disorder, malnutrition, and other relevant. Its clinical manifestations and liver function tests like severe hepatitis. Many anorexia, nausea, vomiting, general discomfort, right upper quadrant pain, decreased fetal movement, obviously bleeding tendency and awareness obstacles to its coma. Not normally associated with fever. Medical and para-examination can be found jaundice, high blood pressure, ascites, edema and renal failure, liver volume can be normal or reduced, ultrasonography showed fatty liver, liver biopsy showed acute diffuse alveolar small hepatic steatosis.