Renault Renault disease and the difference between the phenomenon?

Renault syndrome (Raynaud syndrome) is spastic artery disease is acromegaly small artery spasm caused a series of hand or foot skin color change syndrome. Can be divided into primary and secondary class 2. Essential to that is Renault disease (Raynaud disease), the incidence of the disease associated with any systemic disease or be able to establish the cause of the foundation. Secondary Raynaud's phenomenon, also known as (Raynaud phenomenon), Raynaud's phenomenon that has caused the basis of the disease. Clinical more common and important it is the latter, about the disease 2 / 3. The Raynaud's disease is rare. [Causes] Renault disease etiology is unclear, and may be related to neuroendocrine dysfunction, as in some cases every menstrual heavier. Often patients with family history may also be concerned with genetic. Occur in young women, the male to female ratio of 1:10. Raynaud's phenomenon can be found in many of the primary basis of the disease, the most common is the connective tissue diseases, especially scleroderma. Tough sore systemic erythematosus, vasculitis, rheumatoid arthritis, dermatomyositis, etc. may also occur. Other reasons are: occlusive atherosclerosis, cold hypergammaglobulinemia, neurovascular compression of diseases such as thoracic outlet syndrome, long-term application of vibration of the tool disease, and other diseases such as GAS HAMMER. In addition, the application of certain drugs such as lysergic and beta blockers, etc. can also be caused. Renault phenomenon secondary to connective tissue disease was particularly prevalent in women; men were mostly middle-aged patients with secondary to occlusion of atherosclerosis. [Pathophysiological] Renault syndrome pathophysiological changes can be in three phases: ① spasm ischemic period: that, in the first toe artery spasm, followed capillaries and small veins also cramps, pale skin. ② congestion hypoxic period: artery spasm before receding, the capillary blood, lack of oxygen, skin cyanosis. ③ dilated congestive period: spasm after all the lifting, a dilated congestive vascular reactivity, skin flushing. Then to normal color.