Schistosomiasis

Overview of schistosomiasis (Schisosomiasis) is a parasitic schistosome in the adult human body caused by the way Fang disease is prevalent in Asia, Africa, Latin America's 73 countries, the incidence of the disease is about 2 million. Human schistosome into Schistosoma japonicum (S. japonicum). Egypt schistosomiasis (S haematobium). Schistosoma mansoni (S. mansoni) and the interpolation between schistosomiasis (S intetcalatum) Four . Schistosomiasis is distributed in China, Japan, the Philippines, Indonesia, Thailand and other Asian regions and countries; Man's distribution of schistosomiasis in Asia, the Middle East, India and other areas; Interstitial schistosome distributed in the west central Africa, Zaire, Cameroon and other countries. My only popular Schistosoma japonicum (schistosomiasis). Disease is an ancient disease, 1972 Hunan Changsha Mawangdui Han Dynasty Tomb excavations unearthed from the Han woman (221, 206) and 1975 Hubei Jiangling Phoenix Mountains male body, found in offal schistosome eggs to prove that early in 2100 the disease has already exist. SUI yuan to the nest "written on the causes and symptoms of" Gu Du records "and insanity inflation", from the endemic areas, seasons, infection and clinical performance seems to schistosomiasis. 1904 Japanese scholars Guitian first in the cat's body was found schistosome adult Fujinami 1909 with the Village proved schistosome penetrated the skin in vivo, 1912 ~ 1914 MIYAKAWA, into the palace, Suzuki and other identifying schistosome life cycle. China in 1905 in Changde, Hunan by the egg first diagnosed patients. Schistosomiasis is harmful to people's health the most important parasitic diseases. Liberation initial statistics, about 10 million more than those with 100 million population is infected Granville HS, Beaufort area of nearly 12.8 billion square meters. 13 provinces, municipalities and autonomous regions have the disease distribution. Serious endemic areas, the sick have been killed and sparsely populated, are held, barren fields, "create the 1000 village Thunderbolt Weishi 10,000 people traveling ghosts singing" The tragic scenes. After the liberation of schistosomiasis carried out a large-scale control of the masses of work and achieved great results, not to the 1970s period, the incidence of the disease has dropped to 2.5 million, advanced patients rarely seen. MOLLUSCICIDE area of over 90 million square meters and occupies an area of Beaufort over 80%, preventing a number of innovative research. The majority of schistosomiasis endemic area has undergone a fundamental change. But to achieve the complete elimination of schistosomiasis in the end, also need to make long-term and arduous efforts. Male and female Schistosoma japonicum pathogenic variant, parasitic in humans and animals eventually host the inferior mesenteric vein, Reversible transitional blood worms in the intestinal submucosa peripheral vein. Encirclement of mating male and female worms lay eggs in small branches of small vein, every worm eggs per day in 2000 ~ 3000. Egg was oval, 100 × 70 ~ 50 ~ 60μm, the thin shell without cover, light yellow color, with a lateral small thorn. Intravascular eggs in mature, containing MIRACIDIA, MIRACIDIA cytolytic secretion of substances, through the egg shell into the gut, make the vascular wall damage around mucosal tissue ulceration and necrosis. As intestinal peristalsis, intra-abdominal pressure and intravascular pressure increased, so that the egg with tissue from falling into the lumen. With faeces excreted. After the eggs into the water at 20 ° C for 30 ~ 12 ~ 24 hour incubate MIRACIDIA. swimming in the water MIRACIDIA 1 ~ 2 days, encountered snail (intermediate host) has taken the initiative to invade at the Beaufort liver, lymphatic cavity. Development of the mother sporocyst and daughter sporocyst, after 5 ~ 7 weeks the formation of large cercariae gradually escape Lo vitro, cercariae Yat into the water or out of the river or the shore grass dew China. Contact with the water eventually host cercariae, the cercariae adsorbed on the host's skin, using the secretion of lysosomal protease dissolved skin tissue. tail off into the epidermis into worm boy. Tong invasive pest dermal layer of lymphatic or vascular small to venous system, with the blood flow to the right heart, lung, left heart into the systemic circulation, or lung wear to the chest, through the diaphragm into the abdominal cavity. After about four days after the arrival of mesenteric vein, and moved with the flow of intrahepatic portal system, Initial development after return to the superior mesenteric vein settlers, here, male and female encirclement of sexual maturity, spawning. Cercariae from skin infections to a minimum spawning mating required 23-35 days, usually 30 days. Adults in vivo survival of two-five years or death, in some adult patients could survive more than 30 years.