Tuesday, January 15, 2008

He diabetes and coronary heart disease relationship

Diabetes is a systemic metabolic disorders, which easily gives rise to the fact that coronary heart disease has been recognized by scholars at home and abroad. Analysis of the capital hospital in 1958 ~ 1977 20 1,000 cases of diabetes patients of which 380 cases with coronary heart disease, accounting for 38%, much of our natural population census of the high incidence; Framingham at the age of 36 ~ 62 years of 5,209 people for as long as 20 years studying and observing, The results showed that in diabetic patients, both men and women, different age groups, cardiovascular disease incidence rates are higher than the non-diabetic group diabetic group. After adjusting for age, blood pressure control, smoking, cholesterol and other coronary heart disease risk factors, coronary heart disease, thrombosis-infarction, total cardiovascular disease mortality showed that both male diabetic patients twice in the control group, while women are three times in the control group. Diabetes as a risk factor in coronary heart disease, gender, men with a strong risk of morbidity, However, age-adjusted and control other risk factors for coronary heart disease, Women suffering from diabetes on the risk of coronary heart disease than men, and some even reported that Diabetes is the independent women with coronary heart disease risk factors. Diabetic patients with coronary heart disease because of the increased rate is not very clear. But diabetes easily lead to atherosclerosis has been recognized. Most scholars believe, obesity, hypertension, hyperlipidemia lipoprotein, high blood glucose, Hyperfibrinogenemia (insulin resistance syndrome), these elements are inseparable. Obesity enable the biological role of insulin in some crowd has been weakened, these people have the body to insulin resistance. To ensure normal blood glucose levels, insulin secreting beta cells must be several times higher than normal, or even several tens of insulin, Formation hyperinsulinemia, but ultimately leads to increased blood sugar, elevated blood triglyceride levels, lower HDL  C, increased plasma fibrinogen, which are all atherosclerosis risk factors. Meanwhile, insulin itself also promote atherosclerosis role, therefore, Sulfosalicylic urine oral hypoglycemic agents or insulin injections, and so on through different channels so that blood insulin levels, This makes it possible to further increase the vascular sclerosis lesions. In addition, diabetes patients with coronary heart disease, coronary artery disease in certain clinical symptoms of exposure or later, more clinicians should pay attention. Because of diabetic neuropathy can affect the nervous system of any part of, in particular nerve endings, When a patient's damaged nerve endings, the pain threshold increased, even if there was a serious myocardial ischemia, pain is not a typical minor. not even the symptoms of angina, painless myocardial infarction incidence, but shock, heart failure, Sudden death is also more complications, the more serious the prognosis. Therefore, diabetes patients, the doctors should, under the guidance of science to control blood sugar, and regularly to the hospital to check the heart, be reasonable diet and physical activity to reduce the incidence of coronary heart disease, improve the quality of life of patients.

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