Occult primary glomerular diseases

Cause pathogenesis of glomerular disease occult previously known as misprision of nephritis. The disease is characterized by : the course of faith, and pathological changes slightly less performance, only urine abnormalities, and may cause immune-related. Acute glomerulonephritis, light glomerular nephropathy, hereditary nephritis early, the disease is likely areas. Most clinical onset conceal, cause unknown, and no general edema, hypertension, renal function has changed. Only the abnormal urine changes, the majority of the medical examination and discovered accidentally when diagnosed. The urine disease characterized by abnormal changes : ?٠only a small amount of proteinuria, urinary protein majority "1.0g/24h; Minorities urine protein slightly more, "2.5g/24h without hematuria, a type of particle, often known as "asymptomatic proteinuria." ?ڠrecurrent hematuria, patients usually can be no abnormal urinalysis or only microscopic hematuria, no special symptoms and signs, certain incentives (such as fever, pharyngitis, tiredness, catch cold), affected by a few hours or a few days (mostly in 1 -2 days). had gross hematuria, in the short term (1 -4 days) hematuria disappeared or restored to its original level. If the persistence of microscopic hematuria, a difference of microscopic examination of the urine RBC pleomorphic type, count "10000/ml. No tube, "Simple hematuria." Diagnosis and differential diagnosis of clinical performance as "asymptomatic proteinuria" or "isolated hematuria," no radical past, chronic nephritis, or kidney history, no edema, hypertension dysfunction, blood or biochemical changes, the establishment of basic diagnosis. Subject to the following proteinuria, and other physiological differential. A functional proteinuria high fever, intense physical activity because after renal vascular spasm or pH decrease, glomeruli vascular wall permeability-increasing, it can lead to proteinuria, but disappeared after the removal of etiology, in strenuous exercise, Some patients to the naked eye or microscopic hematuria, but stopped soon after the campaign disappeared. 2, orthostatic proteinuria about 5% of young people in the tower when significant proteinuria, not normally associated with microscopic hematuria. Urinary protein berth disappear, orthostatic proteinuria exact mechanism is not yet clear. Some orthostatic proteinuria glomerular who had abnormal changes. 3, IgA nephropathy in more clinical recurrent hematuria as the main performance, due to upper respiratory tract infection or exhaustion, catch cold after a few hours to several days (most of the 1 -2) Hematuria caused or exacerbated appeared haematuria, eliminating incentives, gross hematuria has disappeared, has returned to the original level, no edema, without hypertension, or blood biochemistry and renal dysfunction. only a small number of patients can be in the form of acute glomerulonephritis syndrome, hypertension, and ultimately the development of renal dysfunction, But still diagnosed by renal biopsy examination (IgA extensive deposition in the glomerular mesangial area). 4, and the attention of urinary tuberculosis, stones, tumors and other identification. Treatment of the disease most stable and does not require special treatment, care should be taken to avoid exertion to catch cold, infection, and strengthen the physical training. Guben also reinstated. Right hematuria or proteinuria more obvious will be the trial of glucocorticoid plus antioxidants (SOD and vitamin E) treatment.