Sunday, January 13, 2008
Rheumatoid Arthritis Clinical treatment
1. General treatment : rest, joint braking (acute phase), joint exercises (recovery), physical therapy. 2. Drug treatment : (a) non-steroidal anti-inflammatory drugs : a selection of species, not using two species. (2) slow-acting antirheumatic drugs : such as methotrexate, sulfasalazine, Auranofin, chloroquine, penicillamine, cyclophosphamide, azathioprine, cyclosporine A, Tripterygium Wilfordii, to be chosen as a condition even more than the two joint application Individual stressed. (3) adrenal cortex hormones : an abuse, only adapt to the outside section or arthritis symptoms obviously not a non-steroidal anti-inflammatory drugs to control or slow-acting drug not effective starting with the persons. 3. Experimental therapy : some preliminary biological agents for the clinical anti-IL - I, anti-tumor necrosis factor, antithrombin CD, Monoclonal antibody and anti-IL - I and anti-tumor necrosis factor receptor antibodies or cytokines in these inhibitors, Upsilon-interferon. 4. The disease should now adhere to Western medicine therapy and, if necessary, the appropriate use of herbal dialectical treatment, adjuvant therapy. 5. Other treatment : Application of discretion Fushekangshuanmei, plasmapheresis, the whole body lymph node irradiation, the local joint administration. 6. Surgical treatment : apply to patients with advanced joint deformities, rigidity, loss of function or aseptic bone necrosis, Drug fails to reverse or improvement. 7. Special complications of treatment : (a) rheumatoid vasculitis : hormones, penicillamine, Poison Control cells and plasma exchange treatment, In recent years, application of intravenous cyclophosphamide and methylprednisolone pulse therapy. (2) Felty syndrome : splenectomy for repeated attacks on the serious infection, thrombocytopenia, anemia, painful splenomegaly, esophageal varices or serious chronic leg ulcers. Drug treatment available Auranofin, methotrexate and cyclosporin A. [Efficacy and discharge standards -- standards for clinical remission following six, at least five of at least two of : 1. Morning stiffness ≤ 15 minutes; 2. No weak; 3. No joint pain; 4. No joint tenderness, pain or activities; 5. Soft tissue swelling and no tendon sheath; 6. ESR male "20 hours and women" 30mm / 1 hour. This standard does not apply to patients with rheumatoid arthritis, acute vasculitis, pericarditis, pleurisy, fever. Achieved clinical remission or improvement in conditions of relative stability will be discharged.
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