Hypoxyradiotherapy reduce cervical cancer side effects

Fourth Military Medical University Xijing Hospital radiation therapy Bureau since 1995 began using low-radiation therapy of cervical cancer, Years of clinical results prove that Hypoxyradiotherapy reduce cervical cancer patients the side effects of radiotherapy and reduce the incidence of complications. Hypoxyradiotherapy in conditions of acute hypoxia cancer radiation therapy as a new approach. As the tumor tissue blood flow was slow, and the lack of blood supply, acute hypoxia low blood oxygen reach the tumor tissue slower, was also relatively small, so the hypoxic state, already in a state of hypoxic tumor tissue oxygen tension from further rapid decline. and normal tissue oxygen tension can be reduced quickly, the normal cells of radiation sensitivity decreases. Use normal tissue and tumor tissue hypoxia response to the time difference, the selection of appropriate hypoxia and the irradiation time, can better protect normal tissue without reducing radiation on the tumor cell-killing effect. Hypoxia is the method of using some of repeat respiratory principle of exhaled gas filter CO2 and water vapor. with some fresh air mixed inhalation, namely the control of gas inhalation of oxygen content, have varying degrees of hypoxia. The Section 80 cases of cervical cancer were randomly divided into Hypoxyradiotherapy group and conventional radiotherapy, two of the 40 cases, adopt brachytherapy and external beam radiotherapy combination of methods, intracavitary irradiation dose fractions of 40 ~ / ~ 8 wk. In vitro radiation dose of 50 Gy / 6 ~ 8 wk. hypoxic hypoxia group wearing breathing apparatus (or oxygen respirator for 10.5% of the hypoxic gas). The results showed that the short-term efficacy of the two groups no significant difference (P "0.05), but the group Hypoxyradiotherapy proctitis, cystitis, Vaginal adhesion incidence of complications was significantly lower than conventional radiotherapy group (P "0.05), Hypoxyradiotherapy group after treatment WBC greater than conventional radiotherapy group (P "0.05).