Saturday, January 12, 2008

Ovarian cancer preoperative chemotherapy can be done

All along, surgical resection is the treatment of ovarian cancer main means it can decide the length of survival time and quality of the effects of chemotherapy. But in fact, surgical resection can Although most tumors, However, some smaller or residual tumor cells must rely on chemotherapy can be the complete elimination of clean, Otherwise, it is very likely for the operation "unraveling." Early ovarian cancer through a comprehensive and accurate staging surgery to determine which patients need chemotherapy. The results showed that low risk of early ovarian cancer (Ia, Ib, high, moderate differentiation) without chemotherapy; high risk of early ovarian cancer (c Ⅰ and Ⅱ period, the low differentiation, cell carcinoma), in patients with advanced ovarian cancer chemotherapy norms. Ovarian cancer Ovarian used early, adequate dose, intermittent approach, that is the body able to tolerate the situation, use adequate amount of chemotherapy drugs, the cancer cells develop resistance, as far as possible, to be killed. At present, domestic commonly used first-line chemotherapy regimen : Platinum + cyclophosphamide or drug Taxol. Although "more cycles of chemotherapy" once considered to be ovarian cancer chemotherapy characteristics, but now appears, excessive chemotherapy (for example, Shibajiu courses) is not desirable, and because they can increase the resistance of tumor cells, but the side effects are great. However, ovarian cancer chemotherapy 6 -8 courses or necessary. Past academic once that ovarian cancer patients in chemotherapy after surgery should be conducted, but the latest results confirm that in ovarian cancer diagnosis, advanced patients can receive a limited course of chemotherapy, then surgery. Because ovarian cancer is discovered, they have already arrived, the tumor widely distributed, large in size, and want to be surgical excision, may be involved small intestine, bladder and other nearby organs, such damage will be very large. If in the pre-operative chemotherapy, it will greatly enhance the surgical resection rate, as far as possible to reduce the damage other organs. improve the therapeutic effects and allow patients to resume as soon as possible. However, preoperative chemotherapy, it must meet three conditions : First, patients ascites cells to be positive, that identified the presence of tumor cells; Secondly, the higher the level of CA125, more sensitive to chemotherapy; Finally, Complete surgical resection of the tumor is unlikely. This is usually chemotherapy every three weeks for a meeting, so 1 -2 courses on it.

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