Saturday, January 12, 2008
Drug treatment of benign prostatic hyperplasia
BPH results of surgical treatment are mostly good, but the operation was not without danger, therefore, For years the medical profession has been actively seeking to replace surgical methods of medical treatment. Although so far, drug cure prostate hyperplasia still very difficult, but drug therapy to alleviate symptoms, delayed surgery time and minimize the occurrence of acute urinary retention have effect. Moreover, the clinical indeed a considerable number of patients with benign prostatic hyperplasia to a certain extent after maintaining stable and not development. Therefore, BPH drug therapy in the treatment of benign prostatic hyperplasia place. The past, clinicians have used androgen, estrogen and androgen and estrogen combined trying to narrow the prostate, But due to a lack of satisfaction with the animal model, coupled with transrectal ultrasound technology to detect prostate ago, Imaging technology is still unable to accurately determined the size of the prostate, the effect of the assessment was considerably affected. Moreover, the side effects of certain drugs, such as estrogen increases breast so, right heart and sexual activity and the impact has been applied to certain restrictions. In recent years, progesterone and other anti - androgen drugs has been more widely used, such anti - androgen drugs. especially Chlormadinone hexanoic acid and ketone Connaught pregnancy is not only the improvement of clinical symptoms, but also transrectal ultrasound detected prostate-shrinking objective basis. Luteinizing hormone releasing similar effects of drug even more certain that medication after six months in blood testosterone equivalent to the level of testicular removal. In recent years, the Finasteride and cernilton is better promote prostate-shrinking drugs. Α adrenergic blocker application in recent years has been great progress. We know that the prostate tissue is the major smooth muscle receptors α1 receptor, Europium receptors found primarily in the vascular smooth muscle. Because of the commonly used phenexybenzamine both α1 and α2 receptor blocking, side effects, it In recent years has been the α1-specific receptor blockers such as high-Te Ling replaced. Α1 receptor blocker with good voiding symptoms improved, reducing residual urine flow rate and increase the role of so popular doctors and patients welcomed. In addition, plant drugs Srinagar-star spent herb, nettle leaf and root, pumpkin seed, Poplar. right BPH is effective, but the mechanism is unclear. Cholesterol lowering agents such as candicidin actinomycin by lowering cholesterol (BPH-cholesterol levels increased twice) is expected reduce prostate hyperplasia, but more side effects. Currently used in the forefront of health, safety and communications urine drug, its pharmacological effects and mechanisms not sure. Kang forefront of pure pollen preparation; On links with a variety of urinary amino acids, may reduce prostate edema. These two drugs beneficial to humans sound, but also has significant placebo effect. Finally, it should be stressed that the drug treatment applies only to the emphasis on obstruction in patients with benign prostatic hyperplasia. have renal dysfunction and in patients with bladder stones should follow doctors advice and decisive surgery, in order to avoid delay in treatment, and lead to serious consequences.
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