Hypertension in the elderly should be careful reserpine

Reserpine is the clinical application of a wide range of anti-hypertensive drugs. The hypotensive effect of the characteristics of slow, moderate, lasting more than 1 week oral appeared, 2 ~ 3 weeks role peak Sustainable withdrawal after 3 ~ 4 weeks. For mild to moderate hypertension early, effective and reliable, and stable. Standing with other antihypertensive agents component compound, the treatment of various types of hypertension. However, long-term use can lead to many adverse reactions, so elderly patients with hypertension, especially should be careful. As the elderly long-term use of reserpine can cause central nervous system and gastrointestinal reactions. Often central role in the performance and stability drowsiness, weakness, fatigue, sometimes a nightmare. Long-term use of low-dose (small to 0.25 mg daily) may also cause depression, serious even attempt suicide. Therefore, if the original spirit of the elderly history of depression banned. If long-term use of large doses of reserpine, dual extrapyramidal symptoms can occur, similar to Parkinson's disease, manifested as muscle tremor, This was due to central basal ganglia dopamine depletion about it. Gastrointestinal reaction mainly to generate increased gastric acid secretion, diarrhea, the elderly suffering from gastric ulcer should be banned reserpine. Application reserpine elderly may emerge after nasal obstruction, heart rate and other symptoms. Long-term can lead to sodium and water retention edema. According to the experts who conducted the survey of adverse drug reaction analysis has found that long-term use of reserpine elderly female patients, their incidence of breast cancer than unmedicated peers Women 3 ~ 4 times. If the aged in the application while taking reserpine digitalis drugs, but also is likely to sudden cardiac arrest or complex arrhythmias. In addition, long-term use of reserpine can inhibit sexual function, mood deterioration of the elderly, depression. Therefore, elderly patients with hypertension do not have to be careful in using or reserpine, especially those with gastrointestinal ulcers, history of depression and heart failure in patients with hypertension, blood pressure should be banned reserpine