An overview of systemic diseases and infertility.

The cause of infertility caused many, in addition to reproductive, endocrine abnormalities and genital abnormalities can lead to infertility, some systemic disease can also induced infertility. The most common is the endocrine and metabolic aspects of diseases, such as hyperthyroidism, thyroid aircraft receded, adrenal cortical dysfunction, such as diabetes and obesity. The first one refers to obesity is due to obesity energy intake and consumption imbalance between, surplus energy in the form of fat accumulation in the body caused weight gain, weighing over ideal body weight or 20% of the body mass index (BMI)> 26 persons. With the modernization level of production and the improvement of people's living conditions, particularly in developed countries, the incidence of obesity increasing, with diabetes, coronary atherosclerotic heart disease, cardiovascular disease, hypertension, hyperlipemia incidence of the disease is closely related. Obesity can lead to abnormal function of ovarian, uterine stunting, infertility, sexual dysfunction and genital. vaginitis other gynecological disorders. Obesity has confirmed that the incidence of infertility patients was significantly higher than those of normal weight. The first two thyroid dysfunction thyroid dysfunction can cause estrogen metabolism. FSH and LH secretion, obviously speaking of ovarian dysfunction and seldom pregnancy. Now for thyroid dysfunction infertility pathological mechanisms no sufficient knowledge the following factors may be relevant : 1, ovarian dysfunction clinical studies show that thyroid function in patients with low gonadotropin secretion was pulse, but the baseline levels were higher than normal. thus the impact of ovulation. Although some patients in vivo normal estrogen levels are normal or near normal menstrual cycle, there are still childless, gonadotropin may reduce the effectiveness or the existence of anti-ovarian role, will also result in ovulation. 2, autoimmune thyroid dysfunction in patients with infertility thyroid antibodies were positive share higher such statement may infertility and autoimmune dysfunction related. 3, metabolic abnormalities in patients with hypothyroidism often the metabolic function and lead to lower obesity, in order to increase the incidence of infertility. 4, the impact of uterine development of the experimental study of low thyroid function in rats uterine structure, endometrial found reduced muscle thinning, reduce the size of the Palais Kok. No. 3 diabetes can be induced diabetic sugar, fat, protein and other substances in vivo metabolism of a variety of functional disorders, female patients often accompanied by menstrual disorders and infertility, pregnancy or after the stillbirth, premature delivery or fetal macrosomia. Diabetes caused female infertility is now the cause is still unknown, reported little. May the following factors : (a) autoimmunity : in some diabetic patients with infertility can be found anti-insulin antibody, some cases may also detected ovarian antibodies. (2) Obesity : Some diabetic metabolic disorder induced by obesity, and obesity is one of the reasons for infertility.