Luteal and habitual abortion

Approximately 35% to 40% of repetitive abortions by luteal insufficiency caused. A cause. Stunting ovarian follicle and corpus luteum formation of defects, and FSH blood shortage or lack of blood and estrogen, progesterone ratio too high, blood did not appear high enough on the LH peak. 2. Luteal Phase endometrial change or delay in the secretory phase is not complete, endometrial in the progesterone receptor leads to endometrial right progesterone effects worse. 3. The endocrine abnormalities, such as hyperprolactinemia, such as hypothyroidism. 4. Endometriosis. 5. Others : as a result of abortion and sterilization as iatrogenic. Pathogenesis normal pregnancy -- when the fertilized egg after 5 to 7 days in endometrial implantation implantation, trophoblast cells begin secreting human chorionic gonadotropin (HCG), HCG stimulation luteal development continue to grow Luteal as pregnancy, progesterone have continued. Six weeks of pregnancy luteal function of the recession, placental trophoblast cells began synthetic progesterone. It pregnancy 6 to 7 weeks at the most vulnerable to abortion. If luteal insufficiency including luteal shortened life expectancy, and luteal secretory dysfunction, as well as progesterone secretion is insufficient. endometrial secretion of adverse reactions or decidua of early pregnancy adverse reaction. caused implantation difficult gestation or development of gestation after implantation be affected, resulting in abortion. Diagnosis -- luteal mainly to the menstrual cycle shortened menstrual but normal, with normal or slightly more, with the history of spontaneous abortion. Often dependent on the support diagnosed. 1. Based on the temperature measured (BBT), the high temperature duplex sustained period of a few days less than 12 days. the average temperature increase below 0.30C, BBT curve in a "ladder-like" has been creeping up, there are indications luteal insufficiency. 2. Curettage of the menstrual cycle in the first 26 days curettage, SCRAPING endometrial tissue examination, observation endometrium is whether the formation of the menstrual cycle and the number of days in line, if endometrial secretion was bad or behind curettage 2d day of endometriosis, then consider luteal insufficiency. 3. Plasma progesterone Determination of pregnancy-luteal phase progesterone plasma level below 6ng/m1; After fertilization, the last menstrual after four weeks should the plasma progesterone 50.50mmol / l; up to seven weeks pregnant 62.08mmol / L, dynamic determination of early pregnancy plasma progesterone and HCG values predictable early abortion and guide treatment. ??-- A treatment. Add progesterone therapy commonly used 20mg, a / d intramuscular injection. Pregnancy does change weekly two to three drugs to stop pregnancy in March, there is a certain effect. Also progesterone vaginal delivery applications, such as love Andean properly gel 300 ~ 500 mg / day. 2. Luteal support therapy for HCG luteal maintain and promote secretion of luteal role the second half of the menstrual period 2000 intramuscular injection every other day, or at ovulation 3,5,7 days after intramuscular injection of HCG 3000U Good results can be achieved. Indeed pregnancy to pregnancy intramuscular injection every other day in February, and progestin therapy also added applications. 3. For follicular development therapy for the treatment of this is right, the better effect, in recent years, more applications. The main use of human menopausal gonadotropin-Cashmere gonadotropin therapy (HMG - HCG therapy) can also be used FSH. HMG for use in the menstrual cycle 3,5,7,9,11 d day, intramuscular application HMG 150U, while monitoring ovulation. When the main follicle average diameter of 18mm HMG out when, 24 hours after intramuscular injection of HCG 5000 ovulation, the absence of ovarian hyperstimulation syndrome, or HCG can be used to maintain progesterone luteal function. Primary hospitals can also choose clomiphene, tamoxifen therapy, but weaker effect, drug can also addressed some of luteal insufficiency. 4. With hyperprolactinemia by the treatment of luteal insufficiency with hyperprolactinemia, available Bromocriptine treatment, 5 mg / d, sub-second oral, PRL dropped when, after natural conception or drug treatment of super ovulation pregnancy. 5. TCM treatment is effective, and the option of luteinizing soup.