Metabolic arthritis (Gout)

Gout (scientific name: metabolic arthritis) is a result of purine (a translation of "Princeton") metabolism, uric acid accumulation caused by disease, a part of arthritis, also known as metabolic arthritis. Women tend gout before age 50 will not happen because of estrogen can inhibit the formation of uric acid; but after menopause increases the attack rate. Since the concentration of uric acid in the blood is too high, the formation of needle-like crystals in the joints and soft tissue, such as a film or tendon, the body's immune system over-reaction leading to (sensitive) and cause painful inflammation. Usually attack sites of the big toe joint (a condition called podagra), ankle and knee. Long-term patients with gout attack in the finger joints, and even cases of soft tissue containing ear portion. Acute gout attack site redness, swelling, heat, pain, and more generally in the midnight attack, make people wake up from sleep. Early gout, seizures more common in the lower extremities.

Disease profile

Gout distributed throughout the world, by race, diet, alcohol consumption, the impact of occupation, the environment and education and other factors. Europe and America gout prevalence of 0.2% to 1.7%. In China, the incidence of gout is rising in recent years, China's general population prevalence rate of about 1.14%, of which Taiwan and Qingdao region is the high incidence of gout, Taiwan's indigenous population over the age of 18 the prevalence rate of about 11.7%. The occurrence of gout associated with gender and age, more common in the elderly, accounting for about 90% of the peak age of onset is 40 to 50 years old, male to female ratio is about 20: 1.

Incentives caused by gout

Hyperuricemia is caused by the main cause of gout. Research indicates that opportunities in men, uric acid concentrations were higher, the higher the emergence of symptoms of gout, uric acid concentrations in excess of 9 milligrams per deciliter who will be 4.9% of gout. Large epidemiological studies in recent years found that gout with alcohol (especially beer) and meat (particularly offal) and related seafood intake, some studies point out carbonated drinks and fructose may also cause gout. On the other hand, vitamin C, coffee and dairy products it is likely to prevent the occurrence of gout help.

Cause alcohol gout is due to alcohol in the liver tissue metabolism, absorbs water, the blood concentration strengthened, so that the already close to saturation of uric acid, accelerated into the soft tissue to form crystals, causing the body's immune system overreaction (sensitive) caused by inflammation . After some food metabolism, which can lead to partial derivatives of the original accumulation of uric acid crystals re-dissolved in soft tissue, and then can induce aggravate arthritis. In addition, strenuous exercise, obesity and stress also lead to increased uric acid levels, induce gout.