Monday, March 24, 2008

How to correct the reversibility of chronic renal failure aggravated factors?

There are some reversible CRF often aggravated factors, If promptly corrected, could reverse the course of disease and improve renal function and prevent or delay the arrival of renal failure.
(1) infections: uremic patients because of the impact of various toxins, poor body resistance, decreased immune function and easy with systemic infection, infection will inevitably further increase renal damage. Therefore, uremic patients rapid deterioration of renal function, unexplained fever, pyuria, and the infection is easy with the primary disease and should be seriously, if active treatment should be found. After infection control with ease uremia, or even able to remove uremic state.
(2) urinary tract obstruction: the upper urinary tract obstruction after increased pressure within the urinary tract, urinary reflux, leading to kidney damage, uremia aggravated obstruction of a timely lift patients can cause obstruction, renal function may have different the degree turn for the better.
(3) hypovolemia: uremic patients because of severe restrictions on sodium and water, plus diuretic, on the lower tubular sodium reabsorption, causing dehydration, resulting in insufficient blood volume, decreased glomerular filtration rate, renal function further damage, if appropriate supplementary blood volume, it can improve symptoms.
(4) Hypertension: due to various reasons uremic patients suddenly increased blood pressure, kidney damage would worsen, so that blood pressure remained at an appropriate level to ensure that both blood pressure and kidney certain filtration rate, renal delay failure development.
(5) acidosis: When a patient CO2-CP lower than 18 mmol / L, in addition to basic drugs, the increase acidosis actively seeking the removal of factors can reduce the symptoms of uremia.
(6) electrolyte imbalance: uremic patients often have low blood calcium, high serum phosphate, calcium deposition in the kidneys, resulting in the continued deterioration of renal function. Also due to inadequate intake of potassium, application diuretics, appeared more hypokalemia and should be dealt with, otherwise would have serious consequences.
(7) The use of kidney toxic drugs: renal failure drug excretion delayed easily in the blood and tissue accumulation, cause kidney damage, the use of these drugs, renal damage aggravated by the drug could be considered.
(8) systemic diseases: chronic uremia primary renal damage can be caused, but also can be secondary to certain diseases or systemic diseases, such as connective tissue diseases, metabolic diseases, such as cardiovascular disease, uremia as for the above diseases caused by, or aggravated due to these diseases, then promptly correct treatment of these diseases can uremia primary condition improved by a degree or completely turn for the better.
(9) excessive protein intake: uremic patients protein content in food, BUN content and the degree of renal dysfunction was parallel relationship. Therefore, protein intake should be based on renal function to determine the situation. 

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