Saturday, January 12, 2008
Non-variceal bleeding treatment
In cirrhosis induced upper gastrointestinal bleeding. Non-varicose veins rupture caused by hemorrhage is about 1 / 3 to 1 / 2. Although bleeding as varicose veins rupture ferocious, but because of complex reasons for bleeding, bleeding sites scattered, confirmed to bring certain difficulties, clinical plant mortality is still high. In the treatment of hemorrhagic measures. A variceal bleeding, compared to both similarities. They also have their own characteristics. (1) therapy with variceal bleeding treatment. (2) lowering drug portal pressure in the non-variceal bleeding etiology. Portal hypertension pieces gastropathy (PNG) hemorrhage caused by about 80% due to portal hypertension PHG the root causes, lower portal pressure on the prevention and treatment of bleeding caused by the PHG important measures. (3) local hemostasis a drug application. Monteggia (Monsell) solution gavage Note Monteggia solution were the main ingredients of Basic ferric sulfate. With strong role in the convergence enables blood coagulation and thrombosis. The bleeding wound and form a layer of protective film brownish-black sky hemostatic effect. 5% of its common solution through a gastric tube into the stomach or sprayed under endoscope. The oral drug is not appropriate, on various occasions when the Department of Membrane easily lead to injury, it should be repeated application invalid replacement of other hemostatic I France. 2. Norepinephrine norepinephrine enable strong local vascular contraction, blood flow and reduce bleeding. 3. Thrombin direct role in the coagulation process of the third stage, prompted blood fibrinogen the fast generation of colloidal state of fibrin clot, to plug the bleeding point to achieve hemostasis purpose efficacy and side effects. Heating thrombin or acidic environment in both easy to lose, and therefore can not be solvent temperature> 37 degrees Celsius, medication given to acid drug better role to play. 4. Prothrombin complex (PPSB) PPSB including prothrombin, coagulation factor WJ and ugly. When cirrhosis SPPSB reduce the synthesis, it can lead to bleeding. By coagulation disorders or liver cell dysfunction induced upper gastrointestinal bleeding, a temporary infusion of PPSB good hemostatic effect. 5. Yunnan Baiyao, March 7 paste Chinese herbs can be oral or gastric tube Chong endoscopic partial sprinkler, with good results in bleeding, no side effects and so on. In the new film erosion gastrointestinal ulcers or bleeding. 6. Only K-dimensional cirrhosis BU gastrointestinal bleeding when available Vitamin K Deficiency and Intervention Among ~ 20 mg intravenous or intramuscular injection. As for the lack of vitamin bleeding, generally can rapidly improve. (4) the control of gastric acid secretion, reduced stomach acid pH in the incidence of gastrointestinal bleeding plays an important role, Thus inhibition of gastric acid secretion and gastric acid which reduce gastric pH were to stop bleeding is important.
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