Saturday, January 12, 2008

How hepatorenal syndrome treatment?

Treatment of hepatorenal syndrome, we should focus on improving liver function and to avoid treatment-induced factors, the specific treatment of the following : (1) to enhance the treatment of liver disease, renal failure occurred avoid : Diuretics caution and avoid large release ascites, Prohibited non-steroidal anti-inflammatory drugs, medicines can inhibit prostaglandin synthesis, inducing the disease. Caution nephrotoxicity drugs, the treatment of active gastrointestinal bleeding. (2) of vasoactive drugs Application : Most scholars believe that lack of effective circulating blood volume based on the start, it still advocates expansion for the trial, including the admission of isotonic saline, plasma, albumin; because of plasma renin activity and angiotensin II were significantly increased, leading to renal vasoconstriction. It has been dopamine antagonists and angiotensin-supercharged muscle-C treatment, but the effect is not yet sure. (3) reinfusion of losers : albumin can be added, increasing colloid osmotic pressure, increase blood circulation volume, the treatment of refractory ascites a certain effect. (4) liver transplantation : the right not reverse liver failure patients, this may be the only effective therapy, to be explored in future efforts.

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