Early cirrhosis and clinical performance

Early clinical cirrhosis means no specific symptoms or signs of liver function tests no obvious abnormalities, but in the liver histology already obvious pathological changes. Chinese and foreign researchers have confirmed that patients with early cirrhosis, liver collagen content of various There has been an increase, which I, type III collagen deposition mainly increased. Advanced cirrhosis to increase mainly Type I, Type III Early mainly with the progress of liver fibrosis. type I / III collagen ratio from 1.59 to 1, type I collagen fibers increased participation in the formation of connective tissue. its reversible strong, mainly seen in advanced liver cirrhosis. As early cirrhosis in clinical no specific signs and symptoms, it is sub-clinical stage of the pathological changes. However, some patients can have the following performance. (1) systemic symptoms : mainly weak, easy fatigue, physical decline. A small number of patients can show facial pigmentation. (2) chronic dyspepsia : Fresh satisfied receded, with constipation or abdominal distension, diarrhea or liver flu, obviously tired. (3) signs : a small number of patients can see spider angioma, liver mild to moderate swelling, were found to have alcohol in patients with cirrhosis, no general tenderness. Spleen may be normal or mildly swollen. These clinical manifestations often easy with the original confused with chronic liver disease or causes attention.