Saturday, January 5, 2008
Drug dermatitis (medicamentosa)
Drugs called dermatitis medicamentosa, drugs by the oral, External and injections to enter human skin and mucosa caused by the inflammatory response. Drug dermatitis on the human body enormous harm. Almost all the drugs may cause dermatitis, the most common iodine amine drugs, anti-inflammatory drugs, sleeping pills and the kind of penicillin, streptomycin, and so on. Epispasis variety of forms, mainly in the following categories : ?Ù fixed drug eruption : The most common type, Every time that the original attack in the same location repeatedly morphogenetic drug dermatitis. Occur in the limbs, trunk and other parts of the lips, particularly genital parts and other styles. When a drug service, the original site of the same rashes, can be increased with the size, location can be increased. urticaria kind medicamentosa : sudden onset, a body symmetry of the distribution. Start with the face and neck, later spread to the extremities and trunk. Pruritus, and patients were chills and fever. - exfoliative dermatitis medicamentosa : This type of a long incubation period, the early measles and to continue the development of skin gradually red, swelling, then leaves with extensive skin-scaling, repeatedly greatly. epidermolysis bullosa epispasis : This epispasis extremely serious, acute onset. Systemic large blisters occur, damage by abrasion after exposing large areas of severe pain erosion surface, such as second-degree burns exposed skin, if not promptly rescue life is in danger. Clinical manifestations : 1. Have a history of drug use, including oral administration, injection, inhalation, and drop their mouths, and found, enema, suppository, and other topical. Initial medication long incubation period, the general incidence 7-10 days. If a patient has already past drug allergies, drug relapse cases after 1-2 days can catch the shortest for a few minutes. 2. External caused by the drug, systemic symptoms not obvious. Oral caused by the drug, often uneven systemic symptoms, such as headache, dizziness, nausea, vomiting, general malaise, chills or fever (such "drug hot" heat varies), and in some cases accompanied by offal (liver, kidney) damage. Diagnosis based on : 1. Disease before medication history; 2. A certain latency; 3. Sudden onset, rashes symmetry, Pan-fat (except for fixed epispasis) colorful; 4. consciously itching; 5. Severe with mucosa, Organs and body symptoms. [Clinical] pure Chinese medicine treatment of this disease in 105 cases, 6-10 days were recovered in 82 cases, The remaining 23 cases, because the course is longer, an average of 25 days cure.
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