Cirrhosis of peptic ulcer-prone What are the reasons?

Cirrhosis of peptic ulcer occurred when the mechanism of the following factors may be relevant. (1) mucosa microcirculatory disorders : portal hypertension, upper gastrointestinal mucosa vein. capillary obstructive expansion clot, microcirculatory disorders, energy metabolism, so the lack of nutrition mucosal cell necrosis, formation of erosion and ulcers, bleeding lesions. So that with chronic venous stasis caused by hypoxia. (2) acid role : liver cirrhosis often increased gastric acid, when portacaval shunt formed, normal exist in portal blood stimulated gastric acid secretion material (such as histamine and 5-HT) is not inactivated by the liver. and directly into the systemic circulation, gastric acid hypersecretion of mucous membrane caused by erosion or ulcer. (3) endotoxemia : portal hypertension, intestinal absorption of endotoxin by collateral circulation directly into the blood circulation, endotoxemia caused caused gastrointestinal bleeding. (4), liver dysfunction : particularly those with hepatorenal syndrome, toxic substances in the body retention, direct damage mucosal barrier, causing upper gastrointestinal mucosal erosion and ulcers or bleeding. (5) infection : Patients with liver cirrhosis, immune dysfunction, extreme infection. Infection can be used as a stress factor, stress is the body, increased sympathetic activity, excessive catecholamine secretion, visceral vasoconstriction, mucosal blood supply, vulnerable to ulcers.