Saturday, January 12, 2008
Children with dilated cardiomyopathy heart failure medicatio
Children with dilated cardiomyopathy caused by chronic heart failure for pediatric cardiovascular worker or a big challenge. Which can be found in children of all ages can be found in various reasons, such as infection, immune response, Mitochondrial metabolic disorders. For the treatment of such children with the main purpose is to improve myocardial contractility, reducing the pressure and heart capacity load, reduce pulmonary and systemic venous congestion, prevent the formation of thrombi thrombosis and treatment of complications such as arrhythmia to relieve symptoms and improve the quality of life of children, extend the survival time of patients. But the treatment programs are derived from adult mass conclusion of the study. This includes the application of diuretics to reduce the cycle of lung congestion, Application of angiotensin-converting enzyme inhibitor (ACEI) to expand blood vessels and regulate the structure of ventricular reconstruction, Application of digoxin to increase cardiac contractility, which can increase children's physical stamina and reduce the mortality of children. but it is very difficult to restore normal function. Beta-blockers were introduced in recent years in the treatment of the disease, Several large adult clinical trials confirmed the drug in the treatment dilated cardiomyopathy caused by the failure effective, however, pediatric treatment experience is very limited, however, comes from the adult experience and the limited application of pediatric experience, In other conventional treatment methods do not work, beta-blockers can be cautious as pediatrics dilated cardiomyopathy caused heart failure treatment. The following is a summary by dilated cardiomyopathy caused by chronic heart failure treatment methods : (a) increasing myocardial contractility : Digoxin; (2) reducing the HIR : furosemide; (3) expansion of vascular : ACEI; (4) the regulation of myocardial remodeling : ACEI; (5) reducing the role of catecholamines : beta-blockers; (6) anticoagulant therapy : Warfarin; (7) antiarrhythmic : Under specific circumstances; (8) If treatment fails, mechanical equipment instead of cardiac function in heart transplant wait.
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