Saturday, February 23, 2008

Is seborrheic keratosis senile plaques

Also known as seborrheic keratosis elderly wart disease, senile plaques and basal cell papilloma, A benign skin tumors. Most occur in the elderly, although young people can be seen, but generally occurred in 30-40 age. The past, that the disease is a delayed epithelial moles, benign epithelial tumors, older skin, or changes in infectious diseases, but so far exact cause unknown. Some reports particular emphasis on family dominant inheritance. Clinical manifestations of the disease most common in the face, scalp, trunk, upper limbs, but can also occur in any part of the surface. Early damage to small and flat, the patch realm clear, smooth surface or slightly papilloma-shaped, yellowish brown. After the damage gradually increased, the surface was more tumor-like nipple, forming a layer of fat and thick callus. Pigmentation can be very significant. The color variation old great damage, a skin-color or short, even black. Hair follicle angle is an important feature of the suppository, and sometimes even small early rash In other words, it sees very clearly that the greater the damage to the surface from verrucous many small and flat papillary tumor-like damage from polymerization. Very thick crust formation damage, lightly surface crust Paper, a papillary tumor-like surface. Although the damage sustained grease-like surface, but there are many dry surface damage was verrucous. As superficial damage, it is like adhesive in the epidermis. The disease can be single, but usually more hair, the number of lesions can be many. Symptoms usually not consciously, sometimes itching. When the oil spill occurred in parts of friction or trauma sites, rash can be stimulating and epithelial tissue inflammation and irregular hyperplasia, also known as the stimulation of seborrheic keratosis. Damage occurred on the scalp, does not affect hair growth. The course usually slow, damage to the peripheral expansion, but also integration into large pieces. No self-healing tendencies. Although the report can be complicated with basal cell tumor, but seldom see, it is generally not considered to be precancerous lesions. Pathological changes from the pathology of the disease can be divided into three types, namely keratosis type, spine and adenoid hypertrophic layer type. The three often mixed exist. III have in common is the excessive keratosis, the spine of hypertrophy and tumor-like papillary hyperplasia. The features of the tumor lesions in the basal surface of the same level, the two ends connected with the normal epidermis. Spine - cell hypertrophy can be divided into two kinds of cells for the spine or squamous cell and the other for the basal-like cells, similar epidermal basal cells, such basal-like cells characteristic of this disease is. 3 changes also vary keratosis keratosis - are excessive and tumor-like papillary hyperplasia more notable, and spine of hypertrophy not obvious because of horny invagination of the results, so many false horny cyst formation. Spike hypertrophic layer keratosis are excessive and tumor-like papillary hyperplasia were lighter, although the foreseeable horny cyst, but more pronounced thickening of skin, the skin lesions are often thickened rough reticular formation, thickened epidermal basal cells in more than squamous cell. Adenoid-thin beam to strip from the majority of epidermal cells, such beam of the epidermis to the dermis by extension, and branches or cutting each other; bundle of cells by more than two-tier composed of basal cells. This type of keratocyst rare. Contained within the tumor cells with various types of pigment vary keratosis not obvious increase of pigment, the pigment-adenoid more spine while the number of hypertrophic layer mixed. If the disease combined with clinical and pathologic diagnosis is not difficult. But some early damage like flat wart; keratosis in the exposed parts of damage easy and senile keratosis (or solar keratosis of the disease) confused; pigment deep damage with nevus cells moles distinction. The inflammation or damage may stimulate similar basal cell or squamous cell carcinoma tumors and malignant melanoma, this time for biopsy or surgery required after pathological examination to identify. The disease generally does not require treatment, but only the beauty issue. If itching or inflammation, or diagnosis of a problem, or surgical resection. In addition, the available liquid nitrogen, carbon dioxide frozen treatment, but if not yet clear diagnosis, the best treatment for a biopsy first, so as to avoid misdiagnosis.

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