The treatment of acute leukemia in children principle

The chemotherapy of acute leukemia in children is based on the principles of options, as far as possible, adopt a strong induction chemotherapy programs, joint use, adequate, intermittent, alternately, long-term treatment approach. Leukemia treatment of the fundamental purpose is to enable long-term disease-free survival of patients until cured. Therefore, to be followed in the treatment of acute leukemia classification by type of program to use the principle of selection of the best current chemotherapy program at home and abroad to improve the quality of complete remission, and promptly formal effective complete remission after treatment of leukemia and central nervous system prevention and treatment, we will strive for the greatest possible number of patients cured. (1) combination: synergies can reduce relapse, remission and long-term survival rates improve. (2) adequate administration: In induction phase of the consolidation of the drug enough to kill the greatest number of leukemia cells, bone marrow suppression quickly reached state in the future to reduce the recurrence is extremely important. (3) the type administration: different types of leukemia in the treatment programs are different, they should be of Treatment. (4) intermittent chemotherapy: Intermittent between the two treatment facilitate the resumption of normal hematopoietic cells, and in the telogen entered the proliferation of leukemia cells cycle of chemotherapy in the next easily be killed. (5) long-term treatment: prevent relapse and improve long-term survival rates. For several years in the chemotherapy and chemotherapy can be summarized into two basic programs: ① remission induction therapy (including differentiation therapy); ② remission after treatment (including the consolidation treatment, intensive therapy, and maintenance therapy in the prevention of extramedullary leukemia).