Chronic lymphocytic leukemia diagnosis standards

(1), history and symptoms ⑴ history question: slow onset, patients have no obvious symptoms, history-taking should pay attention to whether there is a fever, night sweats, vulnerable performance. ⑵ clinical symptoms: fatigue, weight loss, lack of appetite, night sweats, physical decline, fever, sometimes skin itching. (2), physical examination found Systemic lymphadenopathy, quality Medium hard, movable, mutual adhesion advanced integration; mildly enlarged liver and spleen, advanced significantly enlarged spleen. Bone pain not obvious. Advanced skin visible bleeding point. (C), auxiliary inspection 1. Blood: are cell anemia is pigment. WBC count> 10 × 109 / L, classification: lymphocyte> 50%, the absolute value> 5.0 × 109 / L; mature lymphocyte predominance, we can see that naive lymphocytes and different types of lymphocytes. Platelet normal or reduced. 2. Bone marrow as: hypertrophic extremely active to active, mature lymphocyte proliferation obviously, accounting for more than 40 percent of the original, naive lymphocytes <10%.>