Saturday, November 3, 2007

What are the specific classification of emphysema?

According to the acinar affected by the disease (terminal bronchiole distal lung tissue) sites to classification. All lobular type (PAE) affects all acinar, lobular Central (CLE) in the respiratory bronchiole and its environs. CLE smokers is the most common type of emphysema, lung and the upper part of at the bottom front of the more serious lesions. the focal PAE smokers accompanied CLE, mainly located in the lung at the bottom. smoking emphysema patients simply CLE 25%, simply PAE of 25%, mixed 50%. mild CLE, pitting the original increase, disease severity, the elastic protein also disappear. in PAE, elastic protein continued to decrease, but no loss of impact. in mild CLE, gas cavity tends to reduce compliance, but in PAE, increase compliance. Distal acinar emphysema (spacing side or pleural under emphysema) in the pleura or under the leaves along the fiber spacing occurred. Ms Chang did not damage the lung, it can maintain good lung function, unless there many serious localized lesions. This type of emphysema often occurred in pulmonary apex, leading to the youth of spontaneous pneumothorax, the lungs and can lead to great big bubble. Bullous ≥ 1 cm in diameter that the gas chamber. Bullous can become very large and full of side chest. Bullous can be completely hollow cavity or gas for the lung tissue of a local cable through serious emphysema. General bullous emphysema is not a part of, and very few big oppression to neighboring serious damage to the lung tissue and lung function . The gas chamber with increased fibrosis, emphysema formally known as the scar, the scar may be the neighboring non-coherent lesions, or may be clinically important and serious, the merger fibrosis diseases such as tuberculosis, silicon calmly disease or sarcoidosis. Anatomical emphysema classification have little clinical significance. However, the different regions of the lungs a good site, and the connective tissue in different capacity - suggested that the relationship between pressure etiology and pathogenesis of different. Different forms of emphysema and lung damage embodies the stereotype reaction.

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