Friday, January 11, 2008
Nephrotic syndrome which common complication?
(1) infections : Due to the large volume of immunoglobulin from urine loss, reduced plasma protein affect antibody formation. Adrenal cortical hormones and cells in the use of poisons, so patients with systemic resistance decreased vulnerable to infection, such as skin infections, primary peritonitis, respiratory infections, urinary tract infections, sepsis and even evoked. (2) of coronary heart disease : nephrotic syndrome patients often hyperlipidemia and high blood coagulation and therefore prone to coronary heart disease. It was reported nephrotic syndrome patients the incidence of myocardial infarction were higher than 8 times. Coronary heart disease nephrotic syndrome has become the third cause of death factors (after infection and renal failure). (3) thrombosis : nephrotic syndrome patients prone to thrombosis. especially membranous nephropathy rate of up to 25% to 40%. Blood clotting reasons edema, less patient activity, intravenous stasis, high blood cholesterol, blood viscosity so concentrated, excessive levels of fibrinogen and v, vii ??actor increased and the use of corticosteroid and prone to high blood coagulation status. (4) acute renal failure : nephrotic syndrome because of the large number proteinuria, hypoproteinemia, hyperlipidemia, the body is usually hypovolemia and hypercoagulability ¨ District vomiting, diarrhea, the use of anti-hypertensive drugs and diuretics large diuretic, kidneys can make blood perfusion dramatically reduced, thereby enabling lower glomerular filtration rate, leading to acute renal failure. Furthermore, nephrotic syndrome renal interstitial edema, protein concentration formed tubular pipe plug type and other factors, also induced acute renal failure. (5) electrolyte and metabolic disorders : the repeated use of diuretics or unreasonable to ban long-term salt nephrotic syndrome can be made in patients with hyponatremia; the use of adrenal hormones and diuretics lead to a large number of large urination, if 92.11%, prone to hypokalemia.
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